(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4,5,6,7-tetrafluoro-1H-indol-3-yl)propanoic acid CAS 281655-59-2
| CAS No. | 281655-59-2 |
| Molecular Formula | C26H18F4N2O4 |
| Molecular Weight | 498.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4,5,6,7-tetrafluoro-1H-indol-3-yl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4,5,6,7-tetrafluoro-1H-indol-3-yl)propanoic acid (CAS 281655-59-2), molecular formula C26H18F4N2O4 and molecular weight 498.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4,5,6,7-tetrafluoro-1H-indol-3-yl)propanoic acid (C26H18F4N2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C26H18F4N2O4 |
| Molecular Weight | 498.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Melphalan Flufenamide (CAS 380449-51-4)
- N-(2,3-dichlorophenyl)-2-((4-phenyl-5-((p-tolylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332907-22-9)
- 1-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[5-(3-nitrophenyl)-1H-pyrazol-3-yl]piperidine (CAS 1025724-72-4)
- N-(3-chloro-4-methylphenyl)-2-((5-(((4-chlorophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 338430-29-8)
- 2-Hydroxy-2’-methylacetophenone (CAS 145070-48-0)
- 5-Nitrobenzo[d]oxazole-2-carbohydrazide (CAS 50486-35-6)
- 2-(3-Amino-4-bromo-1h-pyrazol-1-yl)-N-cyclopropyl-N-methylacetamide (CAS 1248979-99-8)
- (1-(tert-butoxycarbonyl)-5-(4-(tert-butoxycarbonyl)piperazine-1-carbonyl)-1H-indol-2-yl)boronic acid (CAS 913388-55-3)
- 2-Piperazin-1-yl[1,3]oxazolo[5,4-b]pyridine (CAS 300552-26-5)
- 2-((2-Chlorophenyl)sulfinyl)-N-(4-(4-chlorophenyl)thiazol-2-yl)acetamide (CAS 338959-66-3)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-methylpyridine (CAS 1807016-67-6)
- 4-([1,1'-Biphenyl]-4-yl)-6-bromo-2-phenylpyrimidine (CAS 1800229-08-6)
- Carbic Anhydride (CAS 129-64-6)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com