2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)acetamide CAS 28228-40-2
| CAS No. | 28228-40-2 |
| Molecular Formula | C6H12ClNO2 |
| Molecular Weight | 165.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)acetamide (CAS 28228-40-2), molecular formula C6H12ClNO2 and molecular weight 165.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)acetamide is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12ClNO2 |
| Molecular Weight | 165.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(2-Chloro-4-methylphenyl)acetonitrile (CAS 1000554-63-1)
- 4-Chloro-3,5-dimethylbenzonitrile (CAS 1097629-24-7)
- 5-Chloro-1-methyl-1H-indole (CAS 112398-75-1)
- 2-chloro-5-methoxy-pyridin-4-ol (CAS 1196145-74-0)
- 2-Chloro-N-(3-hydroxypropyl)propanamide (CAS 1211481-04-7)
- 2-Chloro-4,5-dimethylbenzonitrile (CAS 1242339-03-2)
- 3-Chloro-1-methyl-1H-indole (CAS 124589-41-9)
- 5-Chloro-2-methoxypyridin-3-ol (CAS 1261365-86-9)
Recommended Standards
- 2-Chloro-5-ethylbenzonitrile (CAS 67648-09-3)
- 2-Chloro-N-(2-ethoxyethyl)acetamide (CAS 321861-48-7)
- 2-Chloro-3,5-dimethylbenzonitrile (CAS 90537-12-5)
- 2-Chloro-n-(2-methoxyethyl)propanamide (CAS 923225-03-0)
- 7-Bromo-3-(trifluoromethyl)benzofuran (CAS 1824663-62-8)
- N-(5-Methylisoxazol-4-yl)butyrimidamide (CAS 122686-21-9)
- 6-(2-(Cyclohex-1-en-1-yl)ethyl)-4-(thiophen-2-yl)-3,4,6,7-tetrahydro-1H-pyrrolo[3,4-d]pyrimidine-2,5-dione (CAS 946325-49-1)
- Cilazapril impurity 1 (CAS CATO-C4X-29771)
- 5-(pyridin-4-yl)-1H-pyrazol-3-amine hydrochloride (CAS 1586784-92-0)
- Pioglitazone impurity 36 (CAS CATO-C4X-138336)
- 3-((4-Chlorophenoxy)methyl)-4-methoxybenzohydrazide (CAS 438221-68-2)
- 4-Hydroxy-2-methoxy-N-methylbenzamide (CAS 1190090-24-4)
- 2-(Pyridin-4-yl)thiazol-4-amine (CAS 89401-67-2)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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