Entacapone impurity 45 CAS 2824922-39-4
| CAS No. | 2824922-39-4 |
| Molecular Formula | C15H11Cl2N3O4 |
| Molecular Weight | 368.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Entacapone impurity 45 (C15H11Cl2N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Entacapone impurity 45 (CAS 2824922-39-4) is a certified pharmaceutical impurity reference standard with the molecular formula C15H11Cl2N3O4 and a molecular weight of 368.17 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Entacapone impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11Cl2N3O4 |
| Molecular Weight | 368.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Entacapone Standards
- Entacapone Impurity 61 (CAS CATO-C4X-162961)
- Entacapone Impurity 63 (CAS CATO-C4X-162963)
- cis-Entacapone-3-sulfate Sodium Salt (CAS 158069-74-0)
- Entacapone Impurity 60 (CAS CATO-C4X-162960)
- Entacapone impurity 50 (CAS CATO-C4X-162950)
- Entacapone Impurity 62 (CAS CATO-C4X-162962)
- Entacapone impurity 49 (CAS CATO-C4X-162949)
- Entacapone impurity 51 (CAS CATO-C4X-162951)
Recommended Standards
- 951891-89-7 3,4-Dimethoxy-2'-iodobenzophenone MFCD07775701 (CAS 951891-89-7)
- N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-2-fluorobenzamide (CAS 1021105-01-0)
- tert-Butyl 6-cyano-3-iodo-1H-indole-1-carboxylate (CAS 2007920-44-5)
- Methyl 8-bromo-2-morpholino-4-oxo-4H-chromene-6-carboxylate, 97% (CAS 1296271-33-4)
- Meropenem Impurity 32 (CAS CATO-C4X-130932)
- Drotaverin Impurity 66 (CAS CATO-C4X-243566)
- Finerenone Impurity 4 (CAS 2640280-86-8)
- (3-(4-Chlorophenoxy)phenyl)methanol (CAS 72714-63-7)
- 7-Bromo-1H-indol-2-amine hydrochloride (CAS 2416262-96-7)
- 2-Amino-N-(3,5-dimethyl-1h-pyrazol-4-yl)-4-methylpentanamide (CAS 1187446-13-4)
- 2-(2-chloroethyl)-1-methyl-imidazole (CAS 1202458-93-2)
- 5-Methoxy-6-(trifluoromethyl)indoline (CAS 178896-79-2)
- 2-[4-(propan-2-yl)phenyl]-1,3-thiazole-4-carboxylic acid (CAS 115311-26-7)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com