Entacapone Impurity 63 CAS CATO-C4X-162963
| CAS No. | CATO-C4X-162963 |
| Molecular Formula | C19H22N2O6 |
| Molecular Weight | 374.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Entacapone Impurity 63 (CAS CATO-C4X-162963), a pharmacopoeial impurity reference standard (molecular formula C19H22N2O6, MW 374.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Entacapone Impurity 63 (C19H22N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O6 |
| Molecular Weight | 374.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Entacapone Standards
- Entacapone Impurity 61 (CAS CATO-C4X-162961)
- Entacapone impurity 45 (CAS 2824922-39-4)
- cis-Entacapone-3-sulfate Sodium Salt (CAS 158069-74-0)
- Entacapone Impurity 60 (CAS CATO-C4X-162960)
- Entacapone impurity 49 (CAS CATO-C4X-162949)
- Entacapone impurity 51 (CAS CATO-C4X-162951)
- Entacapone impurity 46 (CAS CATO-C4X-162946)
- Entacapone impurity 47 (CAS 1402714-31-1)
Recommended Standards
- Nitrendipine EP Impurity C (CAS 21829-28-7)
- Nifedipine Impurity 5 (CAS 21829-26-5)
- Lenalidomide Impurity 33 (CAS CATO-C4X-190333)
- Nimodipine Impurity 37 (CAS 39562-18-0)
- Anastrozole EP Impurity D (CAS 1027160-12-8)
- Pibrentasvir impurity 4 (CAS CATO-C4X-28934)
- Cefpodoxime Proxetil Impurity 34 (CAS CATO-C4X-157934)
- 4-Fluoro-5-methyl-2-nitrobenzonitrile (CAS 1806475-43-3)
- n-(1-(5-Chlorothiophen-2-yl)ethyl)-4-fluorobenzamide (CAS 1183995-74-5)
- 3-(3-Nitrophenyl)benzo[f][1,4]oxazepin-5(4H)-one (CAS 866050-58-0)
- Megestrol Acetate EP Impurity E (CAS 982-89-8)
- 2-(Dimethylamino)isonicotinic Acid Hydrochloride (CAS 1311315-47-5)
- Fluocortolone Impurity 6 (CAS 36130-02-6)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com