2-(4-Chlorophenyl)-6-nitro-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole CAS 282523-33-5
| CAS No. | 282523-33-5 |
| Molecular Formula | C21H13ClF3N3O3 |
| Molecular Weight | 447.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chlorophenyl)-6-nitro-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole.
2-(4-Chlorophenyl)-6-nitro-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (CAS 282523-33-5), molecular formula C21H13ClF3N3O3 and molecular weight 447.79 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-Chlorophenyl)-6-nitro-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (C21H13ClF3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 447.79 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorophenyl)-6-nitro-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H13ClF3N3O3 |
| Molecular Weight | 447.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(3-Chlorophenyl)-6-nitro-1-{[3-(trifluoromethyl)phenyl]methoxy}-1H-1,3-benzodiazole (CAS 303149-40-8)
- 2-(4-Chlorophenyl)-6-nitro-1-((4-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (CAS 400074-02-4)
- 6-[1-(3-Chlorophenyl)-1H-pyrazol-5-yl]-4-methyl-2-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 477709-54-9)
- 5-((4-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 158712-21-1)
- 5-((3-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 158712-46-0)
- 4-(4-(4-Chlorophenyl)-5-((2,6-dichlorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 476483-79-1)
- (4-chlorophenyl)(3-{[(2,4-dichlorophenyl)sulfanyl]methyl}-1-benzofuran-2-yl)methanone 338411-47-5 KS-000035U8 (CAS 338411-47-5)
- 5-(2-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-2-phenyltetrahydro-4H-pyrrolo[3,4-d]isoxazole-4,6(5H)-dione (CAS 308101-49-7)
Recommended Standards
- Methylene Glycol Bis(2,3-dibromopropyl) Ether (CAS 34446-11-2)
- 2-(4-Chlorobenzoyl)-3-{[(2,6-dichlorophenyl)sulfanyl]methyl}-1-benzofuran (CAS 338424-04-7)
- 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N'-(thiophene-2-carbonyl)-4,5-dihydroisoxazole-3-carbohydrazide (CAS 338399-57-8)
- (E)-[(2E)-2-(4-Chlorobenzenesulfonyl)-3-(dimethylamino)prop-2-en-1-ylidene][(2,6-dichlorophenyl)methoxy]amine (CAS 338395-34-9)
- 4'-Acetyl-2'-methyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 178313-44-5)
- 4-bromo-N-(3,4-dimethoxyphenyl)benzenesulfonamide (CAS 332354-59-3)
- 4-(Aminomethyl)-3-ethylbenzonitrile (CAS 202522-07-4)
- (S)-4-Benzylmorpholine-2-methanamine (CAS 186293-55-0)
- 3-Amino-N-mesityl-4-methoxybenzamide (CAS 1016694-77-1)
- 1-(Benzo[d][1,3]dioxol-5-yl)-N-(cyclopropylmethyl)methanamine (CAS 1094392-46-7)
- 2-(Difluoromethyl)-4-hydroxy-3-nitropyridine-5-acetic acid (CAS 1806884-36-5)
- Methyl 3-(4-(2-(1H-1,2,4-triazol-1-yl)propanoyl)-1H-1,2,3-triazol-1-yl)thiophene-2-carboxylate (CAS 478041-14-4)
- 5-(3-Chlorophenyl)-3-phenylisoxazole (CAS 146537-67-9)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
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