2,3-Bis(bromomethyl)pyrazine CAS 282528-30-7
| CAS No. | 282528-30-7 |
| Molecular Formula | C6H6Br2N2 |
| Molecular Weight | 265.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,3-Bis(bromomethyl)pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,3-Bis(bromomethyl)pyrazine (CAS 282528-30-7), molecular formula C6H6Br2N2 and molecular weight 265.93 g/mol, is a CATO reference standard with documented purity and traceability.
2,3-Bis(bromomethyl)pyrazine (C6H6Br2N2) contains a nitrile group, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H6Br2N2 |
| Molecular Weight | 265.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2,5-Bis(bromomethyl)pyrazine (CAS 60023-30-5)
- 2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid (CAS 1803692-75-2)
- 4-(Bromomethyl)-3-(difluoromethyl)-6-hydroxypicolinaldehyde (CAS 1805088-69-0)
- 2-(Bromomethyl)-4-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde (CAS 1805091-89-7)
- 1-Bromomethyl-4-nitro-naphthalene (CAS 16855-41-7)
- 55715-03-2 4-Bromomethyl-3-nitrobenzoic acid Benzoic acid, 4-(bromomethyl)-3-nitro- BNBA (CAS 55715-03-2)
- 2-(Bromomethyl)-6-(3-fluorophenyl)pyridine (CAS 1227511-54-7)
- 2-[4-(Bromomethyl)phenyl]-5-fluoropyridine (CAS 1257426-56-4)
Recommended Standards
- 2-(Dibromomethyl)-5-methylpyrazine (CAS 79081-84-8)
- 2,3-Dibromo-5,6-dimethylpyrazine (CAS 98142-06-4)
- 2-(2,2-Dibromoethenyl)-5-methylfuran (CAS 940098-74-8)
- 2,3-Dibromoanisole (CAS 95970-22-2)
- 5-Methoxy-1,3-dimethyl-2-thiocyanatobenzene (CAS 5285-96-1)
- 4-Methoxyoxepino[3,2-d]isoxazole (CAS 133708-03-9)
- 6-Tert-butyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 4138-19-6)
- Methylophiopogonanone B (CAS 74805-91-7)
- 2-Amino-5-benzylidene-1-methyl-1H-imidazol-4(5H)-one (CAS 6964-11-0)
- 5-Amino-2-hydroxynicotinamide (CAS 1250505-04-4)
- n-Methyl-4-(sulfamoylmethyl)benzamide (CAS 1247384-67-3)
- 2-Methoxy-N-methylbenzamide (CAS 3400-35-9)
- Rasagiline Impurity 20 (CAS 1166392-42-2)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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