Vonoprazan Impurity 37 CAS 2827733-27-5
| CAS No. | 2827733-27-5 |
| Molecular Formula | C11H8FNO |
| Molecular Weight | 189.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Vonoprazan Impurity 37 (CAS 2827733-27-5) is a certified pharmaceutical impurity reference standard with the molecular formula C11H8FNO and a molecular weight of 189.19 g/mol.
Vonoprazan Impurity 37 (C11H8FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Vonoprazan Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO |
| Molecular Weight | 189.19 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Fumarate Impurity 3 (CAS 881674-56-2)
- Vonoprazan Impurity 38 (CAS 2827733-28-6)
- Vonoprazan Impurity 304 (CAS 57331-00-7)
- Vonoprazan Impurity 87 (CAS CATO-C4X-102087)
- Vonoprazan Impurity 57 (CAS 2726830-13-1)
- Vonoprazan Fumarate Impurity 19 (CAS 161958-62-9)
- Vonoprazan Fumarate Impurity 33 (CAS 881674-58-4)
- Vonoprazan Impurity 204 (CAS 4810-41-7)
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