Cloperastine Impurity 3 CAS 6954-45-6
| CAS No. | 6954-45-6 |
| Molecular Formula | C13H11ClO |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cloperastine Impurity 3 (C13H11ClO) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Cloperastine Impurity 3 (CAS 6954-45-6), a pharmacopoeial impurity reference standard (molecular formula C13H11ClO, MW 218.68 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cloperastine Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11ClO |
| Molecular Weight | 218.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Cloperastine Standards
- Cloperastine Impurity 5 (CAS 75842-85-2)
- Cloperastine Impurity 2 (CAS 4960-10-5)
- (R)-Cloperastine (CAS 132301-91-8)
- Cloperastine (CAS 3703-76-2)
- Cloperastine Impurity 1 (CAS 5630-78-4)
- Cloperastine impurity 8 (CAS 132301-89-4)
- Cloperastine Hydrochloride (CAS 14984-68-0)
- (S)-Cloperastine Fendizoate (Levocloperastine Fendizoate) (CAS 220329-19-1)
Recommended Standards
- Bedaquiline Impurity 67 (CAS 345949-37-3)
- Clofazimine Impurity 13 (CAS CATO-C4X-207113)
- Meclozine EP Impurity B (CAS 119-56-2)
- 1-Chloro-3-(4-methylphenoxy)benzene (CAS 89869-16-9)
- Doxepin EP Impurity C HCl(Mixture of Z and E Isomers) (CAS 2887-91-4)
- Etizolam Impurity 12 (CAS 67727-22-4)
- Argatroban Impurity 87 (CAS CATO-C4X-100787)
- 6-Bromo-1,1-dimethyl-2,3-dihydro-1H-isoindole (CAS 1368153-67-6)
- 4-(1-(4-Chlorophenyl)-1-(4-fluorophenyl)but-3-yn-1-yl)-4H-1,2,4-triazole (CAS 88557-58-8)
- N-(1,2,3-Thiadiazol-4-ylcarbonyl)-N-[3-(trifluoromethyl)phenyl]thiourea (CAS 341965-41-1)
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- 1-(3-Ethyl-1-methyl-1h-1,2,4-triazol-5-yl)-3-methylbutan-1-amine (CAS 1342355-81-0)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com