3-(Hydroxymethyl)-4-(2,2,2-trifluoroethoxy)benzaldehyde CAS 2830620-92-1
| CAS No. | 2830620-92-1 |
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-(Hydroxymethyl)-4-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 2830620-92-1) is a high-purity analytical reference standard with the molecular formula C10H9F3O3 and a molecular weight of 234.17 g/mol.
The molecular framework of 3-(Hydroxymethyl)-4-(2,2,2-trifluoroethoxy)benzaldehyde (C10H9F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related Hydroxymethyl Standards
- 5-(hydroxymethyl)-2-(trifluoromethyl)-Benzoic acid methyl ester (CAS 1567667-05-3)
- Methyl 4-(hydroxymethyl)-2-(trifluoromethyl)benzoate (CAS 959632-21-4)
- 3-(Hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 443776-76-9)
- 1-Benzyl-6-(hydroxymethyl)-2,5-piperazinedione (CAS 1353497-53-6)
- 5-(4-(Hydroxymethyl)phenyl)thiophene-2-carboxylic acid (CAS 1245631-37-1)
- 5-(3-(Hydroxymethyl)phenyl)thiophene-2-carboxylic acid (CAS 1349715-82-7)
- 3-(3-(Hydroxymethyl)phenyl)thiophene-2-carboxylic acid (CAS 1349715-93-0)
- 5-(3-(Hydroxymethyl)phenyl)thiophene-3-carboxylic acid (CAS 1349718-52-0)
Recommended Standards
- 3-(4-Nitrophenyl)isoxazole-5-carboxylic acid (CAS 899820-05-4)
- 3,3,3-Trifluoro-2-hydroxy-2-(m-tolyl)propanoic acid (CAS 81182-31-2)
- 3-(2-(Trifluoromethyl)phenoxy)propanoic acid (CAS 926219-09-2)
- 3,3,3-Trifluoro-2-hydroxy-2-(p-tolyl)propanoic acid (CAS 81170-24-3)
- 2-(3-Methoxyphenyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 791600-98-1)
- 2-(3-Cyano-5-methylphenyl)acetic acid (CAS 1261674-95-6)
- 6-Boc-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 259809-44-4)
- Cyclopropyl(2,7-diazaspiro[3.5]nonan-2-yl)methanone (CAS 1784618-79-6)
- (1S)-2,2,2-Trifluoro-1-(4-phenylphenyl)ethylamine (CAS 1228568-45-3)
- 1-(4-Bromo-1H-pyrazol-1-yl)cyclopropane-1-carboxylic acid (CAS 1935387-65-7)
- 3-Bromo-2-hydroxypropanoic acid (CAS 32777-03-0)
- 3-(4-Fluorophenyl)-5-methyl-1h-pyrazole (CAS 475982-42-4)
- N-(prop-2-en-1-yl)oxolan-3-amine (CAS 1342601-29-9)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com