3-Bromo-2,6-difluorobenzoic Acid CAS 28314-81-0
| CAS No. | 28314-81-0 |
| Molecular Formula | C7H3BrF2O2 |
| Molecular Weight | 237.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-2,6-difluorobenzoic Acid (CAS 28314-81-0) is a high-purity analytical reference standard with the molecular formula C7H3BrF2O2 and a molecular weight of 237.00 g/mol.
3-Bromo-2,6-difluorobenzoic Acid (C7H3BrF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Bromo-2,6-difluorobenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3BrF2O2 |
| Molecular Weight | 237.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 5-Bromo-3,4-difluoro-2-hydroxybenzaldehyde (CAS 1206969-61-0)
- 2-Bromo-3,6-difluorobenzoic acid (CAS 124244-65-1)
- 3-Bromo-4,5-difluorobenzoic Acid (CAS 1244642-73-6)
- 3-Bromo-2,5-difluorobenzoic acid (CAS 1520538-81-1)
- 2-Bromo-3,4-difluorobenzoic Acid (CAS 170108-05-1)
- 4-Bromo-2,6-difluorobenzoic Acid (CAS 183065-68-1)
- 6-Bromo-2,3-difluorobenzoic acid (CAS 183065-72-7)
- 5-Bromo-2,3-difluoro-4-hydroxybenzaldehyde (CAS 1895190-72-3)
Recommended Standards
- 3-Bromo-2,4-difluorobenzoic acid (CAS 651026-98-1)
- 3-Bromo-4,6-difluorobenzoic Acid (CAS 28314-83-2)
- 2-Bromo-4,6-difluorobenzoic acid (CAS 651026-99-2)
- 4,6-Dichloro-5-nitropicolinic acid (CAS 850544-26-2)
- (2,4-Dichloro-6-(trifluoromethyl)phenyl)hydrazine (CAS 107047-29-0)
- 4-[3-(4-Fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine (CAS 861209-71-4)
- 3-Amino-N-(4-bromo-3-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-33-4)
- 5-Iodo-N-(4-methoxyphenyl)-2,6-dimethylpyrimidin-4-amine (CAS 677749-50-7)
- 2-(2-Chloro-5-(difluoromethyl)-3-hydroxypyridin-4-yl)acetic acid (CAS 1805391-58-5)
- 4-((Dimethylamino)methyl)piperidin-4-ol (CAS 695145-47-2)
- 5-(Pyridin-3-yl)thiophene-2-carboxylic acid (CAS 278803-20-6)
- 2,2,3,3,3-Pentafluoropropanal (CAS 422-06-0)
- 6-(Furan-2-yl)-1,3-dimethyl-1h-pyrazolo[3,4-b]pyridine-4-carbohydrazide (CAS 937598-55-5)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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