Lasmiditan Impurity 6 CAS 28314-80-9
| CAS No. | 28314-80-9 |
| Molecular Formula | C7H3F3O2 |
| Molecular Weight | 176.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lasmiditan Impurity 6 (CAS 28314-80-9), a pharmacopoeial impurity reference standard (molecular formula C7H3F3O2, MW 176.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lasmiditan Impurity 6 (C7H3F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 176.09 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3F3O2 |
| Molecular Weight | 176.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
Related Lasmiditan Standards
- Lasmiditan Impurity 19 (CAS 1903-67-9)
- Lasmiditan Impurity 1 (CAS 79538-29-7)
- Lasmiditan Impurity 32 (CAS 3355-39-3)
- Lasmiditan Impurity 33 (CAS CATO-C4X-247833)
- Lasmiditan Impurity 4 (CAS 103640-16-0)
- Lasmiditan Impurity 8 (CAS 517875-04-6)
- Lasmiditan Impurity 5 (CAS 68947-43-3)
- Lasmiditan Impurity 2 (CAS 613678-03-8)
Recommended Standards
- 2,4,5-Trifluorobenzoic Acid (CAS 446-17-3)
- 2,3,6-Trifluorobenzoic Acid (CAS 2358-29-4)
- 2,3,5-Trifluorobenzoic Acid (CAS 654-87-5)
- 2,3,4-Trifluorobenzoic Acid (CAS 61079-72-9)
- Fospropofol Impurity 7 (CAS 250345-80-3)
- Nefopam Impurity 33 (CAS CATO-C4X-283733)
- Mianserin EP Impurity B (CAS CATO-C4X-13698)
- 1-Amino-4-hydroxy-2-methoxyanthracene-9,10-dione (CAS 2379-90-0)
- 3-(Benzyloxy)-2-methoxypropan-1-amine (CAS 176848-23-0)
- <I>N</I>,<I>N</I>′-dimethyl-1,6-hexanediamine (CAS 13093-04-4)
- Methyl 2-(1-bromoethyl)benzoate (CAS 16281-95-1)
- 4-cyclopropyl-1H-imidazol-2-amine hydrochloride (CAS 1803598-15-3)
- 3-Ethyl-2-methyl-1H-indole-5-carboxylic acid (CAS 860360-01-6)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com