Venetoclax Impurity 132 CAS 2832347-33-6
| CAS No. | 2832347-33-6 |
| Molecular Formula | C15H11FN2O3 |
| Molecular Weight | 286.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Venetoclax Impurity 132 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Venetoclax Impurity 132 (CAS 2832347-33-6, C15H11FN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H11FN2O3, Venetoclax Impurity 132 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H11FN2O3 |
| Molecular Weight | 286.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
- Venetoclax Impurity 3 (CAS 1235865-75-4)
- Venetoclax Impurity 108 (CAS CATO-C4X-2495108)
- Venetoclax Impurity 110 (CAS CATO-C4X-2495110)
- Venetoclax Impurity 120 (CAS CATO-C4X-2495120)
- Venetoclax Impurity 127 (CAS CATO-C4X-2495127)
- Venetoclax Impurity 128 (CAS CATO-C4X-2495128)
- Venetoclax Impurity 129 (CAS CATO-C4X-2495129)
- Venetoclax Impurity 131 (CAS 2832008-67-8)
Recommended Standards
- Venetoclax Impurity 18 (CAS CATO-C4X-249518)
- Venetoclax Impurity 94 (CAS CATO-C4X-249594)
- Venetoclax Impurity 95 (CAS CATO-C4X-249595)
- Sulfamonomethoxine-13C6 (CAS 1416768-32-5)
- Trametinib Impurity N9 (CAS 871700-41-3)
- Mesna EP Impurity E (CAS 1391054-56-0)
- Maprotiline EP impurity B HCl (CAS 2724727-05-1)
- (R)-2,5-bis(((benzyloxy)carbonyl)amino)pentanoic acid (CAS 13594-49-5)
- 2,3-Dihydro-1H-inden-1-amine sulfate (CAS 936474-09-8)
- Methylene green zinc chloride double salt (CAS 224967-52-6)
- N-(3-(3-Hydroxyprop-1-yn-1-yl)pyridin-2-yl)pivalamide (CAS 1203499-45-9)
- Tert-butyl 4-(3-fluoro-4-methoxyphenyl)-3-hydroxypiperidine-1-carboxylate (CAS 1354951-11-3)
- Thiazole-4,5-dicarbonitrile (CAS 98027-78-2)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com