Sunitinib Impurity 53 CAS 283584-52-1
| CAS No. | 283584-52-1 |
| Molecular Formula | C8H6FN3O |
| Molecular Weight | 179.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sunitinib Impurity 53 (CAS 283584-52-1), a pharmacopoeial impurity reference standard (molecular formula C8H6FN3O, MW 179.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H6FN3O, Sunitinib Impurity 53 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sunitinib Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6FN3O |
| Molecular Weight | 179.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sunitinib Standards
- Sunitinib Impurity 37 (CAS CATO-C4X-133337)
- Sunitinib Impurity 20 (CAS 879274-72-3)
- Sunitinib Impurity 5 (CAS 5434-29-7)
- Sunitinib Impurity 58 (CAS 17106-12-6)
- Sunitinib Impurity 85 (CAS 17106-16-0)
- Sunitinib Impurity 43 (CAS 14352-65-9)
- Sunitinib Impurity 57 (CAS CATO-C4X-133357)
- Sunitinib Impurity 3 (CAS 2199-51-1)
Recommended Standards
- Methyl 5-cyano-2-fluorobenzoate (CAS 337362-21-7)
- 2,2-difluoro-2-(pyridin-2-yl)acetic acid (CAS 1039621-73-2)
- Methyl 4-Cyano-3-fluorobenzoate (CAS 268734-34-5)
- 2-(Trifluoromethyl)pyridine-4-thiol (CAS 1093954-03-0)
- Olmesartan Impurity 70 (CAS 37830-90-3)
- Toltrazuril Impurity 6 (CAS CATO-C4X-24026)
- Pazopanib Impurity 16 (CAS CATO-C4X-172516)
- 5-Amino-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 68723-22-8)
- (R)-Metolachlor (CAS 178961-20-1)
- 2-Cyano-N-(5-phenyl-1,3,4-oxadiazol-2-yl)acetamide (CAS 73720-15-7)
- 1-Pyrrolidinebutyric Acid HCl (CAS 49637-21-0)
- Ethyl 1H-pyrazole-4-carboxylate hydrochloride (CAS 1242339-75-8)
- Milnacipran Impurity 44 (CAS 105310-28-9)
- D-β-Asp9-Tirzepatide (CAS CATO-CPTD788932)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com