Sunitinib Impurity 85 CAS 17106-16-0
| CAS No. | 17106-16-0 |
| Molecular Formula | C7H8N2O4 |
| Molecular Weight | 184.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Sunitinib Impurity 85 (CAS 17106-16-0), a pharmacopoeial impurity reference standard (molecular formula C7H8N2O4, MW 184.15 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sunitinib Impurity 85 (C7H8N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O4 |
| Molecular Weight | 184.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Sunitinib Standards
- Sunitinib Impurity 58 (CAS 17106-12-6)
- Sunitinib Impurity 5 (CAS 5434-29-7)
- Sunitinib Impurity 20 (CAS 879274-72-3)
- Sunitinib Impurity 37 (CAS CATO-C4X-133337)
- Sunitinib Impurity 43 (CAS 14352-65-9)
- Sunitinib Impurity 53 (CAS 283584-52-1)
- Sunitinib Impurity 1 (CAS 37746-78-4)
- Sunitinib Impurity 12 (CAS CATO-C4X-133312)
Recommended Standards
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- Istradefylline Impurity 16 (CAS CATO-C4X-106116)
- Levofloxacin Impurity 64 (CAS 1607796-83-7)
- Obeticholic Acid Impurity 11 (CAS CATO-C4X-115311)
- Aripiprazole Impurity 87 (CAS CATO-C4X-100887)
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- (1R,2S)-2-(2-(2-nitrophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735275-01-1)
- (2S)-3-[(3,3,3-trifluoropropyl)amino]propane-1,2-diol (CAS 1344922-37-7)
- Hexafluoropropene oxide trimer (CAS 2641-34-1)
- Sulindac EP Impurity C (CAS 32004-67-4)
- 2-(7H-pyrrolo[2,3-b]pyridin-7-yl)acetic acid (CAS 807269-92-7)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com