5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine CAS 2836-43-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2836-43-3
Molecular FormulaC6H5ClF3N3
Molecular Weight211.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine CAS 2836-43-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine.

5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine (CAS 2836-43-3), molecular formula C6H5ClF3N3 and molecular weight 211.57 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 5-(Chloromethyl)-2-(trifluoromethyl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H5ClF3N3
Molecular Weight211.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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Why CATO?