2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 284674-73-3
| CAS No. | 284674-73-3 |
| Molecular Formula | C14H7BrClF3N2 |
| Molecular Weight | 375.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 284674-73-3), a certified reference material (molecular formula C14H7BrClF3N2, MW 375.57 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (C14H7BrClF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7BrClF3N2 |
| Molecular Weight | 375.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
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- 2-((4-Bromophenyl)thio)-1-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)ethan-1-one (CAS 478041-99-5)
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Recommended Standards
- 1-Bromo-8-chloro-3-phenyl-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 1272756-38-3)
- 3-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole (CAS 344277-74-3)
- N-(2-Chloro-4-iodophenyl)-4-fluorobenzamide (CAS 433326-86-4)
- 4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine (CAS 2189684-53-3)
- 7-Bromo-1-((1r,4r)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one (CAS 1228014-09-2)
- (2S,3S)-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-carboxylic acid (CAS 1808323-72-9)
- 4-{[(2-Methylpropyl)amino]methyl}phenol (CAS 448925-28-8)
- 1-((Dimethylamino)methyl)cyclopentane-1-carboxylic acid (CAS 1247857-18-6)
- Pactimibe (CAS 189198-30-9)
- 2-Nitro-10H-phenothiazine (CAS 1628-76-8)
- Methyl 3-(3,5-dimethylphenyl)-3-oxopropanoate (CAS 667460-84-6)
- 2-Amino-6-bromo-4-methylbenzonitrile (CAS 2385515-63-7)
- 2-(4-Bromophenyl)-6-nitrobenzo[d]oxazole (CAS 934330-54-8)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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