3-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole CAS 344277-74-3
| CAS No. | 344277-74-3 |
| Molecular Formula | C14H7BrClF3N2 |
| Molecular Weight | 375.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution, 3-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 375.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole (CAS 344277-74-3) is a high-purity analytical reference standard with the molecular formula C14H7BrClF3N2 and a molecular weight of 375.57 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H7BrClF3N2 |
| Molecular Weight | 375.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 1-Bromo-8-chloro-3-phenyl-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 1272756-38-3)
- 2-Bromo-4-formylphenyl 4-chlorobenzenesulfonate (CAS 431984-61-1)
- (4-Bromo-2-chloro-6-fluorophenyl)-1,1,2,3,3,3-hexafluoropropyl ether (CAS 161045-78-9)
- 1-(3-Bromo-4-chlorophenyl)-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one (CAS 898757-23-8)
- 6-Bromo-N-(4-chlorophenyl)-2,3,4,9-tetrahydro-1H-carbazol-1-amine (CAS 812649-21-1)
- Methyl 2-bromo-3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2244128-36-5)
- 6-Bromo-4-chloro-5-iodothieno[2,3-d]pyrimidine (CAS 1799610-95-9)
- Methyl 3-bromo-5-chloro-4-iodobenzoate (CAS 1160574-80-0)
Recommended Standards
- 2-(4-Bromophenyl)-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 284674-73-3)
- 4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine (CAS 2189684-53-3)
- Synaptamide-d (CAS 946524-43-2)
- N-(2-Chloro-4-iodophenyl)-4-fluorobenzamide (CAS 433326-86-4)
- 5-Methyl-2-(p-tolyl)pyrazolidin-3-one (CAS 17028-79-4)
- 2-(3-Chlorophenyl)-[1,2,4]triazolo[1,5-c]quinazoline (CAS 847783-54-4)
- (R)-tert-Butyl 2,4-dimethyl-1,2,5-thiadiazepane-5-carboxylate 1,1-dioxide (CAS 1956437-93-6)
- 3-Amino-3-(3-methylcyclohexyl)propanamide (CAS 1560987-92-9)
- Cinitapride Impurity 1 (CAS 121873-04-9)
- 1-(Thieno[2,3-b]pyridin-5-yl)ethan-1-one (CAS 18354-57-9)
- 2-chloro-N-methylquinazolin-4-amine (CAS 83260-68-8)
- 2-(2-Chlorophenyl)-8-ethylquinoline-4-carboxylic acid (CAS 667435-74-7)
- Gadobenate Dimeglumine Impurity 2 (CAS 71231-87-3)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com