1-(bromomethyl)-4-(1-fluorocyclopropyl)benzene CAS 2848722-11-0
| CAS No. | 2848722-11-0 |
| Molecular Formula | C10H10BrF |
| Molecular Weight | 229.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(bromomethyl)-4-(1-fluorocyclopropyl)benzene (C10H10BrF) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(bromomethyl)-4-(1-fluorocyclopropyl)benzene (CAS 2848722-11-0), molecular formula C10H10BrF and molecular weight 229.09 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(bromomethyl)-4-(1-fluorocyclopropyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10BrF |
| Molecular Weight | 229.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
Related bromomethyl Standards
- 1-(1-(Bromomethyl)cyclopropyl)-2-fluorobenzene (CAS 1225791-18-3)
- 6-(Bromomethyl)benzo[d][1,2,3]thiadiazole (CAS 1145683-97-1)
- 4-(Bromomethyl)-2,1,3-benzothiadiazole (CAS 16405-99-5)
- 2-(Bromomethyl)thieno[3,2-d]pyrimidine (CAS 77294-18-9)
- 5-(Bromomethyl)-2,1,3-benzothiadiazole (CAS 65858-50-6)
- 5-(Bromomethyl)benzo[d][1,2,3]thiadiazole (CAS 850375-03-0)
- 7-(Bromomethyl)thieno[3,2-d]pyrimidine (CAS 871013-27-3)
- (3R)-3-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS 1142953-55-6)
Recommended Standards
- 1-(4-Bromobut-1-en-1-yl)-4-fluorobenzene (CAS 7515-48-2)
- 1-Bromo-2-fluoro-4-(2-methylallyl)benzene (CAS 951888-47-4)
- 1-(3-Bromobut-3-en-1-yl)-3-fluorobenzene (CAS 731773-06-1)
- 1-Bromo-4-(1-fluorocyclobutyl)benzene (CAS 945717-00-0)
- 21-Butyryloxy Budesonide (CAS CATO-C4X-138913)
- (S)-1-(Cyclohex-1-en-1-yl)-2-(((trimethylsilyl)oxy)methyl)pyrrolidine (CAS 102245-18-1)
- 5-[(4-aminopiperidin-1-yl)methyl]thiophene-2-carboxylic acid (CAS 1174863-10-5)
- p-Hydroxyphenyl propanoate (CAS 3233-34-9)
- 2-(3-((4-Chlorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246811-63-0)
- 2-Benzothiazoleacetic acid, sodium salt (1:1) (CAS 796883-68-6)
- Benzyl (S)-(4-amino-5-hydroxypentyl)carbamate (CAS 82850-42-8)
- Ethyl 3-(2,4-dichlorophenyl)propanoate (CAS 69793-07-3)
- n-(4-Bromo-2-chlorobenzyl)-2-methylpropan-1-amine (CAS 1178687-51-8)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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