3-(4-Chlorophenoxy)pyrrolidine CAS 28491-02-3
| CAS No. | 28491-02-3 |
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(4-Chlorophenoxy)pyrrolidine (CAS 28491-02-3), molecular formula C10H12ClNO and molecular weight 197.66 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Chlorophenoxy)pyrrolidine (C10H12ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-(4-Chlorophenoxy)pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
- (S)-3-(3-chlorophenoxy)pyrrolidine (CAS 1246454-01-2)
- 3-((3-Chlorophenoxy)methyl)azetidine (CAS 1332301-04-8)
- (3R)-3-(2-chlorophenoxy)pyrrolidine (CAS 900572-39-6)
- 1-((4-Chlorophenoxy)methyl)cyclopropanamine (CAS 869535-79-5)
- 3-((4-Chlorophenoxy)methyl)azetidine (CAS 954224-17-0)
- 3-(2-Chlorophenoxy)pyrrolidine (CAS 946715-25-9)
- 3-(3-Chlorophenoxy)pyrrolidine (CAS 337912-67-1)
- 2-(3-Chlorophenoxy)malonaldehyde (CAS 849021-39-2)
Recommended Standards
- 3-(4-Chloro-2-methylphenoxy)azetidine (CAS 954223-36-0)
- 3-(4-Chlorophenyl)morpholine (CAS 909186-38-5)
- 3-(3-Chlorophenyl)pyrrolidin-3-ol (CAS 736879-17-7)
- 3-(Chloromethyl)-N,N-dimethylbenzamide (CAS 442910-26-1)
- 5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde (CAS 343604-31-9)
- N-(3-(6-Oxopyridazin-1(6H)-yl)propyl)-2-phenylethene-1-sulfonamide (CAS 1211969-58-2)
- 5-methylimidazo[1,2-a]pyrimidine (CAS 39567-69-6)
- 1-(2-Fluoro-4-(trifluoromethyl)phenyl)cyclopropane-1-carbonitrile (CAS 1314700-27-0)
- 1-(6-(4-Iodophenyl)-2-methylpyridin-3-yl)ethanone (CAS 1804966-76-4)
- 5-Bromo-2-iodo-1-methoxy-3-methylbenzene (CAS 1887769-55-2)
- (2-(Diethoxymethyl)hept-1-en-1-yl)benzene (CAS 60763-41-9)
- Hydrochlorothiazide-13C6 (CAS 1261396-79-5)
- Tert-butyl n-(1,2-dithiolan-4-yl)carbamate (CAS 1053178-96-3)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com