| CAS No. | 343604-31-9 |
| Molecular Formula | C12H7F3OS |
| Molecular Weight | 256.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde is closely related to sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde (CAS 343604-31-9) is a high-purity analytical reference standard with the molecular formula C12H7F3OS and a molecular weight of 256.24 g/mol.
Owing to sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 256.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C12H7F3OS |
| Molecular Weight | 256.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |