Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate CAS 2853-29-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2853-29-4
Molecular FormulaC8H10N2O4
Molecular Weight198.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate CAS 2853-29-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 198.18 g/mol gives Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate (CAS 2853-29-4) is a high-purity analytical reference standard with the molecular formula C8H10N2O4 and a molecular weight of 198.18 g/mol.

The molecular framework of Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate (C8H10N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10N2O4
Molecular Weight198.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms2

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