Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate CAS 28540-31-0

Description

Compared with other compounds in its class, the molecular weight of 254.33 g/mol gives Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate (CAS 28540-31-0), molecular formula C11H10O3S2 and molecular weight 254.33 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate (C11H10O3S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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