(R)-3-(Chloromethyl)pyrrolidine-1-sulfonyl chloride CAS 2855941-81-8
| CAS No. | 2855941-81-8 |
| Molecular Formula | C5H9Cl2NO2S |
| Molecular Weight | 218.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(R)-3-(Chloromethyl)pyrrolidine-1-sulfonyl chloride (CAS 2855941-81-8), molecular formula C5H9Cl2NO2S and molecular weight 218.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-3-(Chloromethyl)pyrrolidine-1-sulfonyl chloride (C5H9Cl2NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H9Cl2NO2S |
| Molecular Weight | 218.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related R Standards
- 2-Chloromethyl-4-chlorobenzo[d]thiazole, 97% (CAS 110704-20-6)
- 4-(Chloromethyl)-1-(tetrahydro-2H-thiopyran-4-yl)-1H-1,2,3-triazole (CAS 1881291-24-2)
- 2-(4-(Chloromethyl)phenyl)-5-methylpyridine (CAS 1422983-33-2)
- 5-(Chloromethyl)-3-cyclohexyl-1,3-oxazolidin-2-one (CAS 26384-66-7)
- Ethyl 4-(chloromethyl)-5-ethylisoxazole-3-carboxylate (CAS 1119449-80-7)
- 2-(Chloromethyl)-5-cyano-3-(difluoromethyl)-6-hydroxypyridine (CAS 1804486-43-8)
- 2-(Chloromethyl)-4-cyano-3-(difluoromethyl)-5-hydroxypyridine (CAS 1804495-16-6)
- 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)-6-hydroxypyridine (CAS 1805358-61-5)
Recommended Standards
- (3-Cyclopropyl-5-isobutylphenyl)boronic acid (CAS 2225169-44-6)
- 1,3-Dichloro-2-(thiocyanatomethyl)benzene (CAS 7534-64-7)
- (3-(Tert-butyl)-5-cyclopropylphenyl)boronic acid (CAS 2225178-69-6)
- 1,5-Dichloro-2-isothiocyanato-3-methylbenzene (CAS 306935-83-1)
- Ethyl 4-(2-hydroxypropan-2-yl)-2-isobutyl-1H-imidazole-5-carboxylate (CAS 1346598-38-6)
- 4-N-methylpyridine-2,4-diamine (CAS 155617-64-4)
- 2-(4-Chloro-5-fluoropyridin-2-yl)ethan-1-amine (CAS 1393573-01-7)
- Methyl 2-(2-chloroacetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (CAS 300676-39-5)
- 2-(4-Pyrazolyl)ethanol (CAS 180207-57-2)
- n-Cyclopropyl-2-((2-fluoro-4-methylphenyl)amino)acetamide (CAS 923690-42-0)
- Sorafenib impurity 65 (CAS CATO-C4X-112465)
- Tert-butyl 4-(2-fluorobenzamido)piperidine-1-carboxylate (CAS 1233955-45-7)
- Dipyridamole EP Impurity E (CAS 2365420-11-5)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com