Celecoxib Impurity 43 CAS 2860553-70-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2860553-70-2
Molecular FormulaC6H8N4O3S
Molecular Weight216.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Celecoxib Impurity 43 CAS 2860553-70-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 216.22 g/mol gives Celecoxib Impurity 43 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Celecoxib Impurity 43 (CAS 2860553-70-2, C6H8N4O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Celecoxib Impurity 43 (C6H8N4O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Celecoxib Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H8N4O3S
Molecular Weight216.22 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Nitrogen Atoms4
Sulfur Atoms1

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