Celecoxib Impurity 58 CAS CATO-C4X-104358
| CAS No. | CATO-C4X-104358 |
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Celecoxib Impurity 58 (CAS CATO-C4X-104358, C8H12N2O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Celecoxib Impurity 58 (C8H12N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Celecoxib Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O3S |
| Molecular Weight | 216.26 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 56 (CAS 4862-94-6)
- Celecoxib Impurity 28 (CAS CATO-C4X-104328)
- Celecoxib Impurity 43 (CAS 2860553-70-2)
- Celecoxib Impurity 72 (CAS CATO-C4X-104372)
- Celecoxib Impurity 75 (CAS CATO-C4X-104375)
- Celecoxib Impurity 37 (CAS 326-06-7)
- Celecoxib Impurity 71 (CAS CATO-C4X-104371)
- Celecoxib Impurity 1 (CAS 54779-81-6)
Recommended Standards
- Ilaprazole Impurity 152 (CAS CATO-C4X-1130152)
- 6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (CAS 3115-55-7)
- Amoxicillin EP Impurity A(Sulbactam EP Impurity B) (CAS 551-16-6)
- 4-(1H-Benzimidazol-2-yl)-1,3-thiazol-2-amine 7187-47-5 8656AE C10H8N4S (CAS 7187-47-5)
- Droperidol EP Impurity B (CAS 1026015-45-1)
- Valaciclovir Impurity 40 (CAS CATO-C4X-124840)
- Pimavanserin Impurity 48 (CAS CATO-C4X-193848)
- Etrasimod Impurity 63 (CAS CATO-C4X-321463)
- 2-(Aminomethyl)-5-chloro-3-(difluoromethyl)pyridine-6-carboxaldehyde (CAS 1807083-50-6)
- Methyl Ethanesulfonate (CAS 1912-28-3)
- N-Boc-3-(aminomethyl)cyclopentan-1-ol, 97% (CAS 1007306-65-1)
- Tribromide(adenosine-N1)pentaammineruthenium (CAS 63313-47-3)
- tert-Butyl (4-aminocyclohexyl)carbamate hydrochloride (CAS 1269484-61-8)
- Peptide 436 (CAS CATO-CPTD788436)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com