2-(3,4-Difluorophenyl)ethanol CAS 286440-92-4
| CAS No. | 286440-92-4 |
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,4-Difluorophenyl)ethanol (CAS 286440-92-4), molecular formula C8H8F2O and molecular weight 158.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3,4-Difluorophenyl)ethanol (C8H8F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- 1-(2,3-Difluorophenyl)ethanol (CAS 1228690-56-9)
- 2-(2,3-Difluorophenyl)ethanol (CAS 126163-30-2)
- (S)-1-(2,4-Difluorophenyl)ethan-1-ol (CAS 126534-34-7)
- (1r)-1-(2,4-Difluorophenyl)ethan-1-ol (CAS 126534-35-8)
- (1S)-1-(2,5-Difluorophenyl)ethan-1-ol (CAS 126534-36-9)
- (R)-1-(2,5-difluorophenyl)ethan-1-ol (CAS 126534-37-0)
- (S)-1-(2,6-Difluorophenyl)ethanol (CAS 126534-38-1)
- (1R)-1-(2,6-Difluorophenyl)ethan-1-ol (CAS 126534-39-2)
Recommended Standards
- 2-(3,3-Difluorocyclobutyl)-1H-imidazole (CAS 2227205-16-3)
- 2-(3,5-Difluorophenyl)ethanol (CAS 467223-90-1)
- 2-(2,5-Difluorophenyl)ethanol (CAS 862255-56-9)
- 2-(Aminomethyl)-3,5-difluoroaniline (CAS 940054-63-7)
- 6-Ethyl-2-(pyridin-4-yl)quinoline-4-carbonyl chloride (CAS 1203024-76-3)
- 1-(Ethylthio)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1485112-42-2)
- Cyclohexyl(2,5-dimethylphenyl)methanone (CAS 2890-24-6)
- (3-(1H-1,2,3-Triazol-1-yl)azetidin-1-yl)(3,4-difluorophenyl)methanone (CAS 2034265-87-5)
- (4-(Isopentyloxy)phenyl)boronic acid (CAS 1198156-69-2)
- 5-Chloro-2,2-dimethylpentanenitrile (CAS 4207-54-9)
- 2-(Pyrrolidin-1-yl)cyclohexyl (3-(pentyloxy)phenyl)carbamate (CAS 76629-91-9)
- Epinastine Impurity 48 (CAS CATO-C4X-184048)
- Methyl 6-ethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1956331-73-9)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
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