Epinastine Impurity 48 CAS CATO-C4X-184048
| CAS No. | CATO-C4X-184048 |
| Molecular Formula | C30H24Cl2N2 |
| Molecular Weight | 483.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Epinastine Impurity 48 (CAS CATO-C4X-184048, C30H24Cl2N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Epinastine Impurity 48 (C30H24Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 483.43 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H24Cl2N2 |
| Molecular Weight | 483.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Epinastine Standards
- Epinastine Impurity 21 (CAS CATO-C4X-184021)
- Epinastine Impurity 38 (CAS CATO-C4X-184038)
- Epinastine Impurity 47 (CAS CATO-C4X-184047)
- Epinastine Impurity 29 (CAS CATO-C4X-184029)
- Epinastine Impurity 33 (CAS CATO-C4X-184033)
- Epinastine impurity 59 (CAS CATO-C4X-184059)
- Epinastine Impurity 39 (CAS CATO-C4X-184039)
- Epinastine Impurity 23 (CAS 439288-43-4)
Recommended Standards
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 3-(trifluoromethyl)benzoate (CAS 477889-53-5)
- Cefixime Impurity 52 (CAS CATO-C4X-113952)
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-(trifluoromethyl)benzoate (CAS 478040-39-0)
- (2R,3R,4S,5R,6R)-2-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-6-(acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 3180-75-4)
- Cefuroxime Impurity 50 (CAS CATO-C4X-124550)
- Guanfacine Hydrochloride Impurity 1 (CAS 54551-83-6)
- Niraparib Impurity N9 (CAS 1203683-54-8)
- 4-Chloro-2-fluorobenzenesulfonamide (CAS 852664-20-1)
- 1-Amino-4-fluoronaphthalene (CAS 438-32-4)
- 5-Fluoro-1H-benzo[d][1,2,3]triazole (CAS 18225-90-6)
- (S)-4-Benzyl 1-methyl 2-aminosuccinate (CAS 153460-97-0)
- (2,4-Difluorophenyl)(4-methoxyphenyl)methanone (CAS 330670-83-2)
- 2-(3-Chloro-4-methoxyphenyl)acetonitrile (CAS 7569-58-6)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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