5-Bromo-2-(4-bromophenyl)-1H-indole CAS 28718-97-0
| CAS No. | 28718-97-0 |
| Molecular Formula | C14H9Br2N |
| Molecular Weight | 351.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-(4-bromophenyl)-1H-indole.
5-Bromo-2-(4-bromophenyl)-1H-indole (CAS 28718-97-0), molecular formula C14H9Br2N and molecular weight 351.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-(4-bromophenyl)-1H-indole (C14H9Br2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-(4-bromophenyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Br2N |
| Molecular Weight | 351.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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- 2-Bromo-4-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)benzaldehyde (CAS 1779119-56-0)
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- 2-(2-Bromo-4,6-bis(trifluoromethyl)phenyl)acetic acid (CAS 1807217-12-4)
Recommended Standards
- 5,7-Dibromo-2-phenyl-1H-indole (CAS 5326-35-2)
- 6-Bromo-2-(4-bromophenyl)-1H-indole (CAS 28718-96-9)
- 7-Bromo-2-(4-bromophenyl)-1H-indole (CAS 66639-64-3)
- (4-(Fluoromethyl)-5-iodo-6-(trifluoromethoxy)pyridin-2-yl)methanol (CAS 1806741-41-2)
- Ethyl 6-amino-2-(chloromethyl)-5-cyano-4-(1-ethyl-1H-pyrazol-4-yl)-4H-pyran-3-carboxylate (CAS 1005611-67-5)
- Fmoc-β-Ala-Asn(Trt)-OH (CAS CATO-CPTD788475)
- Methyl 2-(3-Oxocyclohexyl)acetate (CAS 2808-12-0)
- 5-Bromo-4-fluoro-2-hydroxybenzaldehyde (CAS 399-00-8)
- 9-(1-Naphthalenyl)phenanthrene (CAS 119925-45-0)
- 2-(1,4-Dimethyl-1H-imidazol-5-yl)ethanamine (CAS 767236-09-9)
- 3-Allyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 857934-96-4)
- 2-(4-Butylphenyl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 932886-61-8)
- Bupivacaine Impurity 13 (CAS 51989-48-1)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
Why CATO?
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