(3S,4S,5R)-4,5-Dimethyl-2-oxo-5-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid CAS 2875066-98-9
| CAS No. | 2875066-98-9 |
| Molecular Formula | C8H9F3O4 |
| Molecular Weight | 226.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3S,4S,5R)-4,5-Dimethyl-2-oxo-5-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (3S,4S,5R)-4,5-Dimethyl-2-oxo-5-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 2875066-98-9), a certified reference material (molecular formula C8H9F3O4, MW 226.15 g/mol) for analytical method development and quality control.
The molecular framework of (3S,4S,5R)-4,5-Dimethyl-2-oxo-5-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid (C8H9F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3S,4S,5R)-4,5-Dimethyl-2-oxo-5-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9F3O4 |
| Molecular Weight | 226.15 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Recommended Standards
- 6-(Difluoromethyl)-3-methyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1806900-30-0)
- 2,3,5,6-Tetrafluoro-4-mercaptobenzoic Acid (CAS 5211-44-9)
- 5-(Difluoromethyl)-4-methyl-3-(trifluoromethyl)pyridin-2-amine (CAS 1806894-58-5)
- 2-Amino-3,5-dinitrobenzamide (CAS 35041-16-8)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-chlorobenzyl)-2-methyl-1H-indole (CAS 400074-09-1)
- 6-Hydroxy-2H-1,4-Benzoxazin-3(4H)-one (CAS 53412-38-7)
- Methyl 3-methyl-5-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxylate (CAS 175276-89-8)
- 8Lambda6-thia-1-azaspiro[4.5]decane-8,8-dione (CAS 1823248-86-7)
- N-(4-(piperidin-1-yl)benzyl)propan-1-amine (CAS 852180-56-4)
- DL-Cyclopentylglycine (CAS 933-95-9)
- 4-FLUOROBENZYL PIPERIDINE-4-CARBOXYLATE HCL (CAS 1135234-93-3)
- 1-(2-Methoxyphenyl)-3-methylcyclopentan-1-ol (CAS 1343937-12-1)
- 2-(Spiro[2.2]pentan-1-yl)acetic acid (CAS 14364-43-3)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
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