(E)-3-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid CAS 2883153-48-6
| CAS No. | 2883153-48-6 |
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 222.63 g/mol gives (E)-3-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-3-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid (CAS 2883153-48-6), molecular formula C10H7ClN2O2 and molecular weight 222.63 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-3-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid (C10H7ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 222.63 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 4-chloroÂbenzÂalhydantoin (CAS 10040-86-5)
- 7-Chloro-2-methyl-8-nitroquinoline (CAS 102653-55-4)
- 1-(2-Chloro-4-nitrophenyl)-1H-pyrrole (CAS 106981-58-2)
- 2-Chloro-7-methyl-6-nitroquinoline (CAS 1092301-48-8)
- 2-Chloro-6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 109274-78-4)
- 4-Chloro-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 1106737-94-3)
- Methyl 2-chloro-1,7-naphthyridine-3-carboxylate (CAS 1124194-70-2)
- 5-Chloro-1-phenyl-1H-pyrazole-3-carboxylic acid (CAS 1137-17-3)
Recommended Standards
- (4Z)-4-[2-(3-Chlorophenyl)hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-one (CAS 338416-83-4)
- 1-(2-Chloro-5-nitrophenyl)-1H-pyrrole (CAS 94033-72-4)
- (2E)-3-{2-chloroimidazo[1,2-a]pyridin-3-yl}prop-2-enoic acid (CAS 2055614-36-1)
- 1-(2-Chlorophenyl)-1H-imidazole-5-carboxylic acid (CAS 893615-79-7)
- (E)-3-hydroxyisobenzofuran-1-carbaldehyde O-(4-chlorobenzyl) oxime (CAS 339023-46-0)
- 2-Oxo-N-(1-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)-1,2-dihydropyridine-3-carboxamide (CAS 1326899-64-2)
- 5,6-Dimethoxy-2-methylbenzofuran-4,7-dione (CAS 158204-26-3)
- 2-(((Benzyloxy)carbonyl)(methyl)amino)-2-phenylacetic acid (CAS 93818-40-7)
- Cis-6-ethyloctahydroindolizine (CAS 112979-79-0)
- 3H-Imidazo[2,1-i]purine, 3-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-, disodium salt (CAS 103213-52-1)
- Opicapone-d6 (CAS 923287-50-7(unlabelled))
- Ethyl 2-bromo-4-methyloxazole-5-carboxylate (CAS 78451-13-5)
- 4-Chloro-N-(cyclopropylmethyl)-2-hydroxy-N-propylbenzamide (CAS 1090638-13-3)
- Peptide 437 (CAS CATO-CPTD788437)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com