(3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(piperidin-1-yl)methanone CAS 288317-51-1
| CAS No. | 288317-51-1 |
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(piperidin-1-yl)methanone (CAS 288317-51-1) is a high-purity analytical reference standard with the molecular formula C16H16ClFN2O2 and a molecular weight of 322.76 g/mol.
The molecular framework of (3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(piperidin-1-yl)methanone (C16H16ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- N-(5-Amino-2-fluorophenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020056-16-9)
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- Cycloxaprid (CAS 1203791-41-6)
- Pim-1 Inhibitor 2 (CAS 477845-12-8)
- 2,5-Diamino-1H-benzo[d]imidazole-7-carboxylic acid (CAS 1804184-34-6)
- 2-Methyl-1-(piperidin-4-yl)-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 503149-66-4)
- 1-(3-Fluoro-4-hydroxyphenyl)propan-2-one (CAS 86615-82-9)
- Esculin (CAS 531-75-9)
- 5-Bromo-n-(2-(tetrahydrofuran-2-yl)ethyl)thiophene-2-sulfonamide (CAS 1258655-91-2)
- 2-(4,6-Dimethoxypyrimidin-2-yl)acetic acid (CAS 66621-86-1)
- 3-Hydroxypropane-1-sulfonamide (CAS 132115-62-9)
- 5-[1-(3-Methoxybenzoyl)pyrrolidin-2-yl]-3-(4-methylphenyl)-1,2,4-oxadiazole (CAS 853366-89-9)
- Ethyl (3S,4S)-4-amino-1-benzylpiperidine-3-carboxylate (CAS 2036041-96-8)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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