6-Chloro-1-iodo-4-isopropyl-2,7-naphthyridine CAS 2883820-95-7
| CAS No. | 2883820-95-7 |
| Molecular Formula | C11H10ClIN2 |
| Molecular Weight | 332.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-1-iodo-4-isopropyl-2,7-naphthyridine (CAS 2883820-95-7), molecular formula C11H10ClIN2 and molecular weight 332.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-1-iodo-4-isopropyl-2,7-naphthyridine (C11H10ClIN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClIN2 |
| Molecular Weight | 332.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-iodopyridine (CAS 1228375-96-9)
- methyl 2-chloro-5-((2,6-dichloropyrimidin-4-yl)amino)benzoate (CAS 1394347-61-5)
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- 5-Chloro-1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 339009-02-8)
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Recommended Standards
- 5-Chloro-1-(3,4-dichlorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 339008-91-2)
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- Resmetirom Impurity 50 (CAS CATO-C4X-291250)
- tert-Butyl 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate (CAS 1202864-54-7)
- Lithium (R)-1-(tert-butoxycarbonyl)aziridine-2-carboxylate (CAS 2173637-01-7)
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- 3-Cyclopropylpiperidine Hydrochloride (CAS 942511-56-0)
- Methyl 2-(2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)benzoate (CAS 332380-81-1)
- tert-Butyl (trans-3-(methylsulfonyl)cyclobutyl)carbamate (CAS 2145004-83-5)
- 2-n-(2-Methylphenyl)-1,3,5-triazine-2,4-diamine (CAS 58759-26-5)
- 1-(7-Methylbenzo[d]oxazol-2-yl)ethanone (CAS 1520573-34-5)
- MB-11362, >98% (HPLC) (CAS 1159183-97-7)
- Darifenacin Impurity 1 (CAS 87776-76-9)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
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