Rosuvastatin EP Impurity F CAS 289042-12-2
| CAS No. | 289042-12-2 |
| Molecular Formula | C29H40FN3O6S |
| Molecular Weight | 577.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 577.71 g/mol gives Rosuvastatin EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Rosuvastatin EP Impurity F (CAS 289042-12-2), a pharmacopoeial impurity reference standard (molecular formula C29H40FN3O6S, MW 577.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Rosuvastatin EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 577.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H40FN3O6S |
| Molecular Weight | 577.71 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 119 (CAS CATO-C4X-1169119)
- Rosuvastatin Impurity 120 (CAS CATO-C4X-1169120)
- Rosuvastatin Impurity 205 (CAS 1007871-85-3)
- Rosuvastatin Impurity 231 (CAS CATO-C4X-1169231)
- Rosuvastatin Impurity 43 (CAS 1378943-63-5)
- Rosuvastatin Impurity 44 (CAS 2758676-77-4)
- Rosuvastatin Impurity 45 (CAS 1821422-50-7)
- Rosuvastatin Impurity 47 (CAS CATO-C4X-116947)
Recommended Standards
- Allisartan Isoproxil Impurity 16 (CAS 439904-79-7)
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- Clopidogrel Impurity 25 (CAS CATO-C4X-102925)
- Prednisone Impurity 8 (CAS CATO-C4X-16948)
- Exemestane Impurity 37 (CAS CATO-C4X-164137)
- Ethyl 2-(cyclopentylamino)benzoate (CAS 1094227-86-7)
- methyl 4-(5-aminopyrazin-2-yl)benzoate (CAS 1021918-64-8)
- N,N-dimethyl-2,3-dihydro-1H-indol-5-amine (CAS 56632-38-3)
- Cefamandole Impurity 33 (CAS CATO-C4X-122133)
- Cyanazine-d5 (CAS 1190003-29-2)
- [2H10]-Vancomycin acetic acid (CAS CATO-C4X-177527)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com