Exemestane Impurity 37 CAS CATO-C4X-164137
| CAS No. | CATO-C4X-164137 |
| Molecular Formula | C27H32O5S |
| Molecular Weight | 468.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 468.60 g/mol gives Exemestane Impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Exemestane Impurity 37 (CAS CATO-C4X-164137), a pharmacopoeial impurity reference standard (molecular formula C27H32O5S, MW 468.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Exemestane Impurity 37 (C27H32O5S) contains a steroid core, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H32O5S |
| Molecular Weight | 468.60 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 1 |
Related Exemestane Standards
- Exemestane Impurity 38 (CAS CATO-C4X-164138)
- Exemestane Impurity 11 (CAS CATO-C4X-164111)
- Exemestane Impurity 35 (CAS CATO-C4X-164135)
- Exemestane EP Impurity J (CAS 1160599-91-6)
- Exemestane Impurity 19 (CAS CATO-C4X-164119)
- Exemestane Diol Impurity (CAS 184972-11-0)
- Exemestane Impurity 5 (CAS CATO-C4X-164134)
- Exemestane EP Impurity I (CAS CATO-C4X-164122)
Recommended Standards
- Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) (CAS 1185168-06-2)
- S-acetyl-PEG6-Boc (CAS 1818294-39-1)
- Biotin-PEG2-C4-alkyne (CAS 1011268-28-2)
- N-Benzyl N-Demethyl Trimebutine-d5 (CAS 1330189-05-3)
- Risperidone impurity 46 (CAS 106266-11-9)
- Mirabegron Impurity 129 (CAS CATO-C4X-1032129)
- Lemborexant Impurity 23 (CAS 3037659-15-4)
- 4-((1H-Pyrazol-3-yl)methyl)thiomorpholine 1,1-dioxide (CAS 701214-23-5)
- 2,4-Bis(hydroxymethyl)pentane-1,5-diol (CAS 6221-56-3)
- 4-Chloro-N-(6-methoxypyridin-3-yl)-2-nitrobenzenesulfonamide (CAS 1022580-32-0)
- (5-Chloro-2-fluorobenzyl)hydrazine (CAS 51859-99-5)
- Mitiglinide Impurity 27 (CAS CATO-C4X-116127)
- Platinum(1+), (2-bromo-5-fluoropyridine-κn)(9-hydroxy-6-methylpyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(1h,6h)-dionato-κn1,κn12)(6-methyl-3-pyridinol-κn1)-, (sp-4-2)-, hexafluorophosphate(1-) (CAS 937379-49-2)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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