Canertinib Dihydrochloride CAS 289499-45-2
| CAS No. | 289499-45-2 |
| Molecular Formula | C24H25ClFN5O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Canertinib Dihydrochloride is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Canertinib Dihydrochloride (CAS 289499-45-2) is a high-purity analytical reference standard with the molecular formula C24H25ClFN5O3HCl and a molecular weight of 522.40 g/mol.
Based on its molecular formula C24H25ClFN5O3HCl, Canertinib Dihydrochloride contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 522.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H25ClFN5O3 2*HCl |
| Molecular Weight | 522.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Canertinib Standards
Recommended Standards
- 1,4-Dihydropyrido[2,3-d]pyrimidin-4-ol (CAS 205926-59-6)
- N-(Furan-2-ylmethyl)-3,4-dimethylaniline (CAS 356092-19-8)
- H-Gly-Gly-Gly-Gly-Ala-OH (CAS 20347-80-2)
- 2-(2,5-Difluoropyridin-4-yl)acetic acid (CAS 1227499-12-8)
- Z-Thr-OH (CAS 19728-63-3)
- Ethyl 4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 187035-81-0)
- 1210347-50-4 Abiesadine I (CAS 1210347-50-4)
- 4-Methyl-N-(pentan-3-yl)pyridin-3-amine (CAS 1340137-87-2)
- (1-Methylpiperidin-4-yl)methanamine hydrochloride (CAS 1185296-75-6)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
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