Pilocarpine EP Impurity A HCl CAS 28958-85-2
| CAS No. | 28958-85-2 |
| Molecular Formula | C11H16N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Pilocarpine EP Impurity A HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 244.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Pilocarpine EP Impurity A HCl (CAS 28958-85-2), a pharmacopoeial impurity reference standard (molecular formula C11H16N2O2HCl, MW 244.72 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pilocarpine EP Impurity A HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O2 HCl |
| Molecular Weight | 244.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pilocarpine Standards
- Pilocarpine EP Impurity C Sodium Salt (CAS 101769-87-3)
- Pilocarpine-d3 HydrochlorideDiscontinued (CAS 1217838-88-4)
- Pilocarpine Nitrate (CAS 148-72-1)
- Pilocarpine Impurity 10 (CAS 2833-30-9)
- Pilocarpine Hydrochloride EP Impurity B (CAS 28406-15-7)
- Pilocarpine Hydrochloride EP Impurity C (CAS 34350-99-7)
- Pilocarpine HCl (CAS 54-71-7)
- Pilocarpine-d3 HCl (CAS 54-71-7 (non-labelled))
Recommended Standards
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- tert-Butyl 4-(hydroxymethyl)benzoate (CAS 143726-85-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com