Arginine Impurity 5 CAS 28958-90-9
| CAS No. | 28958-90-9 |
| Molecular Formula | C6H11N3O2 |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Arginine Impurity 5 (CAS 28958-90-9, C6H11N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Arginine Impurity 5 (C6H11N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H11N3O2 |
| Molecular Weight | 157.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 3 |
Related Arginine Standards
Recommended Standards
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- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
- Olmesartan Impurity 20 (CAS 1347262-29-6)
- Gefitinib impurity 02 (CAS 184475-50-1)
- 3-ethynylimidazo[1,2-a]pyridine (CAS 943320-53-4)
- 6-Amino-1-benzyl-5-(benzylamino)pyrimidine-2,4(1H,3H)-dione (CAS 379725-34-5)
- 3-[4-(pyridin-4-ylmethoxy)phenyl]acrylic acid (CAS 924865-90-7)
- 2-Isopropoxyacetaldehyde (CAS 77342-92-8)
- 8-Oxo-Benzylguanine (CAS 158754-46-2)
- 4-n-Butyl-benzamidine hydrochloride (CAS 29147-98-6)
- Neuropeptide K, porcine (CAS 106441-70-7)
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