4-(2,2,2-Trifluoro-1-((trimethylsilyl)oxy)ethyl)morpholine CAS 289706-46-3
| CAS No. | 289706-46-3 |
| Molecular Formula | C9H18F3NO2Si |
| Molecular Weight | 257.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2,2,2-Trifluoro-1-((trimethylsilyl)oxy)ethyl)morpholine (CAS 289706-46-3), molecular formula C9H18F3NO2Si and molecular weight 257.33 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2,2,2-Trifluoro-1-((trimethylsilyl)oxy)ethyl)morpholine (C9H18F3NO2Si) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H18F3NO2Si |
| Molecular Weight | 257.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- 2,2,2-Trifluoro-N,N-dimethyl-1-((triethylsilyl)oxy)ethan-1-amine (CAS 208331-60-6)
- 2,2,2-Trifluoro-N,N-bis(trimethylsilyl)acetamide (CAS 21149-38-2)
- 2,2,2-Trifluoro-N-(2-(prop-1-en-2-yl)phenethyl)acetamide (CAS 2632991-49-0)
- 2,2,2-Trifluoro-1-(5-methoxy-7-methyl-1H-indol-1-yl)ethan-1-one (CAS 1260832-07-2)
- 4,4,4-Trifluoro-3-(1h-indol-3-yl)butanoic acid (CAS 153233-36-4)
- 2,2,2-Trifluoro-N-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide (CAS 90401-87-9)
- 3,3,3-Trifluoro-2-(5-methyl-1h-indol-3-yl)propanoic acid (CAS 252729-38-7)
- 3,3,3-Trifluoro-2-(6-methyl-1h-indol-3-yl)propanoic acid (CAS 2197052-76-7)
Recommended Standards
- 4-(2-(Benzylamino)propoxy)phenol (CAS 59182-24-0)
- 4-(3-Amino-propyl)-3-oxo-piperazine-1-carboxylic acid tert-butyl ester (CAS 198896-21-8)
- 4-((tert-Butoxycarbonyl)amino)cycloheptane-1-carboxylic acid (CAS 2243505-85-1)
- 4-(4-(4-Methoxyphenyl)-1H-pyrazol-1-yl)piperidine (CAS 902836-36-6)
- trans-4-(2-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1049978-59-7)
- 2-Phenylnaphtho[1,2-d]oxazole (CAS 3574-02-5)
- 6-Bromo-5-iodopyridin-3-ol (CAS 697300-70-2)
- Ethyl 6-(thiophen-3-yl)hexanoate (CAS 890098-02-9)
- (5-Bromopyrazin-2-yl)methanamine (CAS 1369140-94-2)
- S-Indacaterol (CAS 1235445-80-3)
- (S)-3-((2R,3R,4R,5S)-5-allyl-3-hydroxy-4-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)propane-1,2-diol (CAS 871348-10-6)
- 3-Amino-N-(pyridin-3-yl)propanamide (CAS 294889-15-9)
- (S)-Methyl 3-methyl-2-(methylamino)butanoate (CAS 35016-37-6)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com