Lidocaine Impurity 41 CAS 2903-48-2
| CAS No. | 2903-48-2 |
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lidocaine Impurity 41 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lidocaine Impurity 41 (CAS 2903-48-2, C10H11NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lidocaine Impurity 41 (C10H11NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Lidocaine Standards
- Lidocaine Impurity 80 (CAS CATO-C4X-167980)
- Lidocaine Impurity 27 (CAS 5177-35-5)
- Lidocaine EP Impurity H (CAS 1131-01-7)
- Lidocaine Impurity 50 (CAS 27794-54-3)
- Lidocaine EP Impurity D (CAS 7728-40-7)
- Lidocaine Impurity 30 (CAS 21236-54-4)
- Lidocaine Impurity 34 (CAS 29183-14-0)
- Lidocaine impurity 66 (CAS CATO-C4X-167966)
Recommended Standards
- Rebamipide Impurity 59 (CAS CATO-C4X-152359)
- Voglibose impurity 19 (CAS 114761-39-6)
- Ketoprofen Impurity 45 (CAS 1272414-15-9)
- Voglibose Impurity 3 (CAS 83465-22-9)
- Atrasentan Impurity 76 (CAS 1058551-13-5)
- Ornidazole Impurity 7 (CAS 14419-11-5)
- [8-L-β-aspartic acid]Terlipressin (CAS CATO-C4X-21937)
- 2-ethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ol (CAS 1250434-52-6)
- (1-Methyl-3-phenyl-5-tosyl-1H-pyrazol-4-yl)methyl 4-chlorobenzoate (CAS 318247-42-6)
- Levosimendan Impurity 84 (CAS CATO-C4X-130884)
- 2-Cyano-3-(2,4-dimethoxyphenyl)-N-(2-methoxyphenyl)propanamide (CAS 1261000-72-9)
- 4-(Hydroxymethyl)tetrahydropyran (CAS 14774-37-9)
- 2-Bromo-6-methylbenzenesulfonamide (CAS 1261758-21-7)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
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