(2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide CAS 2903922-68-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2903922-68-7
Molecular FormulaC12H15FNO2P
Molecular Weight255.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide CAS 2903922-68-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide.

(2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide (CAS 2903922-68-7) is a high-purity analytical reference standard with the molecular formula C12H15FNO2P and a molecular weight of 255.23 g/mol.

The molecular framework of (2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide (C12H15FNO2P) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2-Fluoro-5-methoxy-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H15FNO2P
Molecular Weight255.23 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentF-containing
Nitrogen Atoms1

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