(4-Amino-3-(difluoromethoxy)phenyl)dimethylphosphine oxide CAS 2903922-86-9
| CAS No. | 2903922-86-9 |
| Molecular Formula | C9H12F2NO2P |
| Molecular Weight | 235.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (4-Amino-3-(difluoromethoxy)phenyl)dimethylphosphine oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(4-Amino-3-(difluoromethoxy)phenyl)dimethylphosphine oxide (CAS 2903922-86-9), molecular formula C9H12F2NO2P and molecular weight 235.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (4-Amino-3-(difluoromethoxy)phenyl)dimethylphosphine oxide is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H12F2NO2P |
| Molecular Weight | 235.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
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- (2-Amino-5-(difluoromethoxy)phenyl)dimethylphosphine oxide (CAS 2750028-82-9)
- 5-Amino-2-(2,2,2-trifluoroethoxy)benzoic acid (CAS 1096332-51-2)
- Amino-(2-trifluoromethoxy-phenyl)-acetic acid (CAS 1101781-50-3)
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- (S)-2-Amino-2-(2-(trifluoromethoxy)phenyl)acetic acid (CAS 1228547-92-9)
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Recommended Standards
- 2,4-Bis(trifluoromethyl)cyclohexanamine (CAS 65934-73-8)
- 3,5-Bis(trifluoromethyl)cyclohexan-1-amine (CAS 58665-71-7)
- 5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione (CAS 88740-57-2)
- 7-Fluoroquinoline-2,3-dicarboxylic acid (CAS 110139-62-3)
- 8-Bromo-5-chloroimidazo[1,5-a]pyridine-6-carbonitrile (CAS 2585650-35-5)
- 4-Iodo-3-(trifluoromethyl)pyridine-5-carbonyl chloride (CAS 1803802-06-3)
- 2-(Diphenylamino)pyrimidine-5-carboxylic acid (CAS 1316216-06-4)
- Pirenoxine (CAS 1043-21-6)
- 4-Nitro-2-(trifluoromethyl)-1H-indole (CAS 1000604-20-5)
- 8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole (CAS 39876-39-6)
- (S)-3-Amino-4-(4-(tert-butoxy)phenyl)butanoic acid (CAS 1335850-58-2)
- n-(Dicyclopropylmethyl)cyclopropanamine (CAS 953718-14-4)
- Methyl 2-(3-(bromomethyl)phenyl)acetate (CAS 104508-22-7)
- Semaglutide impurity 50 (CAS 2773558-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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