1-[4-(Diphenylmethyl)piperazin-1-yl]-2-(thiophen-2-yl)ethan-1-one CAS 291291-92-4
| CAS No. | 291291-92-4 |
| Molecular Formula | C23H24N2OS |
| Molecular Weight | 376.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[4-(Diphenylmethyl)piperazin-1-yl]-2-(thiophen-2-yl)ethan-1-one (CAS 291291-92-4) is a high-purity analytical reference standard with the molecular formula C23H24N2OS and a molecular weight of 376.51 g/mol.
The molecular framework of 1-[4-(Diphenylmethyl)piperazin-1-yl]-2-(thiophen-2-yl)ethan-1-one (C23H24N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24N2OS |
| Molecular Weight | 376.51 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Diphenylmethyl Standards
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Recommended Standards
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