(Z)-2-(5-bromo-2-fluorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one CAS 292169-72-3
| CAS No. | 292169-72-3 |
| Molecular Formula | C16H8BrFN2OS |
| Molecular Weight | 375.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (Z)-2-(5-bromo-2-fluorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (C16H8BrFN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(Z)-2-(5-bromo-2-fluorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 292169-72-3) is a high-purity analytical reference standard with the molecular formula C16H8BrFN2OS and a molecular weight of 375.21 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (Z)-2-(5-bromo-2-fluorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8BrFN2OS |
| Molecular Weight | 375.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Z Standards
- 3-Bromo-3',3''-difluorotrityl alcohol (CAS 845790-82-1)
- 3-Bromo-4',4''-difluorotrityl alcohol (CAS 845790-78-5)
- 4-Bromo-3',3''-difluorotrityl alcohol (CAS 845790-81-0)
- 6-Bromo-3-(3,4-dimethoxyphenyl)-4-methyl-2H-chromen-2-one (CAS 720675-07-0)
- 6-Bromo-4-(5-methylfuran-2-yl)-3-(3-oxobutyl)-1H-isochromen-1-one (CAS 917571-25-6)
- N-(3-((8-Bromo-6-(dimethylamino)-9H-purin-9-yl)methyl)phenyl)formamide (CAS 123811-36-9)
- 2-Bromo-N-(4-methyl-5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide (CAS 922000-88-2)
- 2-Bromo-N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)benzenesulfonamide (CAS 415697-57-3)
Recommended Standards
- Tert-butyl 2-(5-iodopyrimidin-2-yl)pyrrolidine-1-carboxylate (CAS 1817679-13-2)
- 1’,4-Dihydroxy Triazolam (1.0mg/ml in Acetonitrile) (CAS 65686-12-6)
- (4-Bromophenyl)(4,6-dimethoxy-3-methylbenzofuran-2-yl)methanone (CAS 180406-41-1)
- 2-(4-Chlorophenoxy)-2-((5-chloropyrimidin-2-yl)oxy)-1-phenylethanone (CAS 88350-63-4)
- 1-[(tert-butoxy)carbonyl]-6-hydroxy-2,3-dihydro-1H-indole-2-carboxylic acid (CAS 2059932-05-5)
- 3-Chloro-1-(3-phenyl-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)propan-1-one (CAS 478048-66-7)
- Methyl 6-bromo-5-methylbenzo[b]thiophene-4-carboxylate (CAS 2168049-75-8)
- 4-Bromo-1,1':2',1''-terphenyl (CAS 24253-37-0)
- 2-(4-Butylcyclohexyl)-1H-1,3-benzodiazole (CAS 571155-14-1)
- 3,6-bis(methylthio)-1,2,4,5-tetrazine (CAS 1672-34-0)
- 3-Amino-4,4-diphenylbutanoic acid (CAS 380861-91-6)
- 4-Amino-2-chloropyridine (CAS 14432-12-3)
- 2-(Benzo[d][1,3]dioxol-5-yl)-N-isopentyl-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1024448-61-0)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com