4-(1-Amino-2,2,2-trifluoroethyl)phenol CAS 294175-07-8
| CAS No. | 294175-07-8 |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1-Amino-2,2,2-trifluoroethyl)phenol (CAS 294175-07-8) is a high-purity analytical reference standard with the molecular formula C8H8F3NO and a molecular weight of 191.15 g/mol.
Based on its molecular formula C8H8F3NO, 4-(1-Amino-2,2,2-trifluoroethyl)phenol contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 191.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (R)-4-(1-amino-2,2,2-trifluoroethyl)phenol (CAS 1187928-59-1)
- (S)-4-(1-amino-2,2,2-trifluoroethyl)phenol (CAS 1187930-88-6)
- (R)-2-amino-2-(2,4,5-trifluorophenyl)ethan-1-ol (CAS 1212857-75-4)
- (S)-2-amino-2-(2,3,4-trifluorophenyl)ethan-1-ol (CAS 1212986-10-1)
- (S)-2-amino-2-(2,4,5-trifluorophenyl)ethan-1-ol (CAS 1213207-29-4)
- (S)-2-(1-Amino-2,2,2-trifluoroethyl)phenol (CAS 1213413-23-0)
- (R)-2-(1-Amino-2,2,2-trifluoroethyl)phenol (CAS 1213553-42-4)
- (S)-2-Amino-2-(3,4,5-trifluorophenyl)ethan-1-ol (CAS 1213556-08-1)
Recommended Standards
- 3-Nitro-4-(1H-1,2,4-triazol-1-yl)pyridine (CAS 912773-00-3)
- 4-(2,2,2-Trifluoroethoxy)aniline (CAS 57946-61-9)
- 3-Methyl-5-(trifluoromethoxy)aniline (CAS 86256-63-5)
- 4-(2,2-Difluoroethoxy)-3-fluoroaniline (CAS 937598-60-2)
- 5-Nitro-6-(pyridin-3-yl)piperidin-2-one (CAS 368835-84-1)
- N,N'-bis(4-Isopropylphenyl) urea (CAS 113260-74-5)
- Benzo[d]thiazol-5-amine hydrate (CAS 1194783-76-0)
- 5-(3-Chloro-4-methoxyphenyl)furfural (CAS 124014-00-2)
- 1-(Benzyloxy)-4-(bromomethyl)-2-methoxybenzene (CAS 72724-00-6)
- N-Fmoc-4-methyl-L-tryptophan (CAS 2411871-30-0)
- 2-(4-bromo-2-fluorophenyl)-2-methyloxirane (CAS 1545775-87-8)
- Sildenafil Impurity 277 (CAS CATO-C4X-1128277)
- Zinc hydroxide phosphate (CAS 60430-04-8)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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