Osimertinib Impurity 34 CAS 2945220-41-5
| CAS No. | 2945220-41-5 |
| Molecular Formula | C56H66N14O4 |
| Molecular Weight | 999.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Osimertinib Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Osimertinib Impurity 34 (CAS 2945220-41-5), a pharmacopoeial impurity reference standard (molecular formula C56H66N14O4, MW 999.21 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Osimertinib Impurity 34 (C56H66N14O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C56H66N14O4 |
| Molecular Weight | 999.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 31.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 14 |
Related Osimertinib Standards
- Osimertinib Impurity 105 (CAS CATO-C4X-2045105)
- Osimertinib Impurity 23 (CAS CATO-C4X-204523)
- Osimertinib Impurity 7 (CAS 2919324-18-6)
- Osimertinib Impurity 118 (CAS 2564638-97-5)
- Osimertinib Impurity 119 (CAS CATO-C4X-2045119)
- Osimertinib Impurity 115 (CAS CATO-C4X-2045115)
- Osimertinib Impurity 51 (CAS CATO-C4X-204551)
- Osimertinib Impurity 29 (CAS CATO-C4X-204529)
Recommended Standards
- Mupirocin impurity 36 (CAS CATO-C4X-170636)
- Mivacurium chloride Impurity 61 (CAS CATO-C4X-137561)
- Mupirocin Dimer 6 (CAS CATO-C4X-170640)
- Linagliptin Dimer Impurity 6 (CAS CATO-C4X-110150)
- Pinaverium impurity 36 (CAS CATO-C4X-246736)
- Dapoxetine Impurity 64 HCl (CAS CATO-C4X-143964)
- Epinephrine Impurity 13 (CAS 6305-04-0)
- Methyl 5-bromo-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazole-4-carboxylate (CAS 2177259-01-5)
- Muricholic Acid Impurity 22 (CAS 111824-32-9)
- (3E,5E)-4-[(4-Chlorophenyl)amino]-6-(dimethylamino)-1,1,1-trifluorohexa-3,5-dien-2-one (CAS 338393-37-6)
- 5-Methyl-2-phenyl-4-vinyloxazole (CAS 1260677-94-8)
- n-Propyl-3,3,3-d3 Alcohol (CAS 61844-01-7)
- 2,4-Dibromo-3-fluoroaniline (CAS 1253889-53-0)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com