Osimertinib Impurity 118 CAS 2564638-97-5
| CAS No. | 2564638-97-5 |
| Molecular Formula | C56H67N14O4 |
| Molecular Weight | 1000.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Osimertinib Impurity 118.
As a process- or degradation-related impurity, Osimertinib Impurity 118 (CAS 2564638-97-5, C56H67N14O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Osimertinib Impurity 118 (C56H67N14O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 30.5, corresponding to approximately 30 ring(s) or double-bond equivalent(s). With a molecular weight of 1000.22 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Osimertinib Impurity 118 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C56H67N14O4 |
| Molecular Weight | 1000.22 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 30.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 14 |
Related Osimertinib Standards
- Osimertinib Impurity 119 (CAS CATO-C4X-2045119)
- Osimertinib Impurity 105 (CAS CATO-C4X-2045105)
- Osimertinib Impurity 23 (CAS CATO-C4X-204523)
- Osimertinib Impurity 34 (CAS 2945220-41-5)
- Osimertinib Impurity 7 (CAS 2919324-18-6)
- Osimertinib Impurity 29 (CAS CATO-C4X-204529)
- Osimertinib Impurity 115 (CAS CATO-C4X-2045115)
- Osimertinib Impurity 51 (CAS CATO-C4X-204551)
Recommended Standards
- Tris[(3-phenyl-1H-benzimidazol-1-yl-2(3H)-ylidene)-1,2-phenylene]iridium (CAS 888725-36-8)
- 5-((4-Chlorophenyl)sulfinyl)-2-(dimethylamino)-6-methylpyrimidin-4(1H)-one (CAS 19807-96-6)
- Everolimus Impurity 7 (CAS CATO-C4X-11227)
- 4',4''''-(5'-(4-([2,2':6',2''-Terpyridin]-4'-yl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)di-2,2':6',2''-terpyridine (CAS 1185464-11-2)
- Prilocaine Impurity 01 (CAS 103-89-9)
- Gadoteridol Impurity 13 (CAS 192329-72-9)
- Valsartan Impurity 56 (CAS 1353844-75-3)
- Methyl 3-chloro-5h,6h,7h,8h-pyrido[4,3-c]pyridazine-6-carboxylate (CAS 39716-01-3)
- 6-Chloro-[1,2,4]triazolo[1,5-b]pyridazine (CAS 42399-79-1)
- 3,4-Dihydro-1,6-naphthyridin-2(1H)-one (CAS 14757-41-6)
- 2-(2-(Benzo[d][1,3]dioxol-5-ylmethylene)hydrazinyl)-5-ethylthiazol-4(5H)-one (CAS 339061-00-6)
- 5-Bromo-6-fluoro-1-propylbenzoimidazole (CAS 1261940-19-5)
- 5-Chloro-1-methyl-4-nitro-1H-pyrrole-2-carbaldehyde (CAS 1708380-42-0)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com