Trimebutine EP Impurity E HCl CAS 294882-33-0
| CAS No. | 294882-33-0 |
| Molecular Formula | C21H27NO5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Trimebutine EP Impurity E HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Trimebutine EP Impurity E HCl (CAS 294882-33-0), a pharmacopoeial impurity reference standard (molecular formula C21H27NO5HCl, MW 409.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Trimebutine EP Impurity E HCl (C21H27NO5HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H27NO5 HCl |
| Molecular Weight | 409.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trimebutine Standards
- Trimebutine Impurity N4 HCl (CAS 104743-23-9)
- Trimebutine EP Impurity B/Trimethoprim EP Impurity J (CAS 118-41-2)
- Trimebutine Impurity 18 (CAS 118291-70-6)
- Trimebutine-d5 (CAS 1189928-38-8)
- Trimebutine EP Impurity E-d5 HCl (CAS 1286632-72-1)
- Trimebutine Impurity 24 (CAS 16623-25-9)
- Trimebutine-d5 Maleate (CAS 2747914-55-0)
- Trimebutine Impurity 27 (CAS 294882-35-2)
Recommended Standards
- Silodosin Impurity 1 (CAS 175870-21-0)
- Hydroxychloroquine impurity 87 (CAS CATO-C4X-183587)
- Adenosine Cyclophosphate Impurity 3 (CAS 63963-62-2)
- 3-Iodo-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one (CAS 1190316-65-4)
- ethyl 5-methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 712319-10-3)
- 5-Amino-2-(methylsulfonyl)benzonitrile (CAS 1549858-32-3)
- 4-Methyl-5-(pyrrolidin-2-yl)pyridin-2-ol (CAS 1270425-24-5)
- Methyl 2-(cyanomethyl)-3-fluorobenzoate (CAS 230301-82-3)
- Disodium Dihydrogen Ethylenediaminetetraacetate Dihydrate (CAS 6381-92-6)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com