4-Amino-2-(4-amino-1,3-dioxoisoindolin-2-yl)-4-oxobutanoic acid CAS 295357-71-0
| CAS No. | 295357-71-0 |
| Molecular Formula | C12H11N3O5 |
| Molecular Weight | 277.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-Amino-2-(4-amino-1,3-dioxoisoindolin-2-yl)-4-oxobutanoic acid (CAS 295357-71-0) is a high-purity analytical reference standard with the molecular formula C12H11N3O5 and a molecular weight of 277.23 g/mol.
The molecular framework of 4-Amino-2-(4-amino-1,3-dioxoisoindolin-2-yl)-4-oxobutanoic acid (C12H11N3O5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11N3O5 |
| Molecular Weight | 277.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
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- 3-Bromo-2-chlorobenzaldehyde (CAS 1197050-28-4)
- (2E)-5,6-dimethoxy-2-[(3-phenoxyphenyl)methylidene]-2,3-dihydro-1H-inden-1-one 268563-94-6 MS-9201 (CAS 268563-94-6)
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- Isopropyl Anthranilate (CAS 18189-02-1)
- Xylazine-d6 Hydrochloride (CAS 1795020-86-8)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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