3,5-Difluoro-4-hydroxybenzonitrile CAS 2967-54-6
| CAS No. | 2967-54-6 |
| Molecular Formula | C7H3F2NO |
| Molecular Weight | 155.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 155.10 g/mol gives 3,5-Difluoro-4-hydroxybenzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,5-Difluoro-4-hydroxybenzonitrile (CAS 2967-54-6), molecular formula C7H3F2NO and molecular weight 155.10 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3,5-Difluoro-4-hydroxybenzonitrile (C7H3F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 155.10 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,5-Difluoro-4-hydroxybenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3F2NO |
| Molecular Weight | 155.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 1,2-difluoro-3-isocyanatobenzene (CAS 1174233-36-3)
- 2,4-Difluoro-3-hydroxybenzonitrile (CAS 1214373-88-2)
- 2,6-difluoro-4-hydroxybenzonitrile (CAS 123843-57-2)
- 2,3-Difluoro-4-hydroxybenzonitrile (CAS 126162-38-7)
- 2,4-Difluoro-6-hydroxybenzonitrile (CAS 1261793-35-4)
- 1,1-Difluoro-3-nitrobutan-2-ol (CAS 129660-33-9)
- 2,5-Difluoro-3-hydroxybenzonitrile (CAS 1806367-92-9)
- 3,4-Difluoro-2-hydroxybenzonitrile (CAS 186590-34-1)
Recommended Standards
- 3,5-Difluoro-2-hydroxybenzonitrile (CAS 862088-17-3)
- 3,6-Difluoro-2-hydroxybenzonitrile (CAS 344764-39-2)
- 3,4-Difluorophenyl Isocyanate (CAS 42601-04-7)
- 4,6-Difluoro-2H-benzo[d][1,2,3]triazole (CAS 2147718-46-3)
- 3-(1H-Indol-2-yl)-N-phenyl-1H-pyrazole-4-carboxamide (CAS 827318-55-8)
- 5-Iodo-2-deoxycytidine (CAS 611-53-0)
- 2-((Methyl(piperidin-4-yl)amino)methyl)benzonitrile hydrochloride (CAS 1289386-29-3)
- 5'-Uridylic Acid Disodium Salt (CAS 3387-36-8)
- Benfluorex Hydrochloride (CAS 23642-66-2)
- Rac-(1r,6r,7r)-7-(trifluoromethyl)-2-azabicyclo[4.1.0]heptane hydrochloride (CAS 1821707-37-2)
- Zolmitriptan-d6 (CAS 1217644-84-2)
- 3-Methyl-4-({[(4-methylphenyl)methyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338975-78-3)
- ethyl 1-(iodomethyl)-3-[4-(trifluoromethyl)phenyl]-2-oxabicyclo[2.2.2]octane-4-carboxylate (CAS 2703774-37-0)
- Uremic Pentapeptide (CAS 71494-20-7)
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