3,6-Difluoro-2-hydroxybenzonitrile CAS 344764-39-2
| CAS No. | 344764-39-2 |
| Molecular Formula | C7H3F2NO |
| Molecular Weight | 155.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,6-Difluoro-2-hydroxybenzonitrile (CAS 344764-39-2) is a high-purity analytical reference standard with the molecular formula C7H3F2NO and a molecular weight of 155.10 g/mol.
3,6-Difluoro-2-hydroxybenzonitrile (C7H3F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,6-Difluoro-2-hydroxybenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3F2NO |
| Molecular Weight | 155.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 1,2-difluoro-3-isocyanatobenzene (CAS 1174233-36-3)
- 2,4-Difluoro-3-hydroxybenzonitrile (CAS 1214373-88-2)
- 2,6-difluoro-4-hydroxybenzonitrile (CAS 123843-57-2)
- 2,3-Difluoro-4-hydroxybenzonitrile (CAS 126162-38-7)
- 2,4-Difluoro-6-hydroxybenzonitrile (CAS 1261793-35-4)
- 1,1-Difluoro-3-nitrobutan-2-ol (CAS 129660-33-9)
- 2,5-Difluoro-3-hydroxybenzonitrile (CAS 1806367-92-9)
- 3,4-Difluoro-2-hydroxybenzonitrile (CAS 186590-34-1)
Recommended Standards
- 3,5-Difluoro-4-hydroxybenzonitrile (CAS 2967-54-6)
- 4,6-Difluoro-2H-benzo[d][1,2,3]triazole (CAS 2147718-46-3)
- 3,5-Difluoro-2-hydroxybenzonitrile (CAS 862088-17-3)
- 4,7-Difluoro-3H-imidazo[4,5-c]pyridine (CAS 855006-72-3)
- tert-Butyl 9-hydroxy-3-azabicyclo[3.3.1]nonane-3-carboxylate (CAS 389890-40-8)
- 6-Bromo-4-(difluoromethyl)-5-fluoronicotinic acid (CAS 1806059-74-4)
- 3-Methoxyisoquinolin-5-amine (CAS 1374652-73-9)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phthalazin-1(2H)-one (CAS 303148-44-9)
- Ethyl 5-(2-bromoacetyl)isoxazole-3-carboxylate (CAS 104776-74-1)
- VU 0155069 (CAS 1781834-89-6)
- 2-(1-Ethyl-1h-imidazol-2-yl)butanoic acid (CAS 1339250-75-7)
- [1-[[(3S)-3-fluoropyrrolidin-1-yl]methyl]cyclopropyl]methanol (CAS 2708341-87-9)
- Ethyl 4-(ethylamino)benzoate (CAS 42265-58-7)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com